![]() Current therapies for LUT dysfunction after SCI focus on preventing complications and managing symptoms rather than restoring function. SCI disrupts both motor and sensory function and leads to marked abnormalities in urine storage and emptying. Micturition is a neurologically complex behavior that depends on intact sensory and motor innervation. However, lower urinary tract (LUT) dysfunction is universal among SCI patients and significantly impacts their health and quality of life. It is commonly assumed that restoration of locomotion is the ultimate goal after spinal cord injury (SCI). 8Faculty of Science, The Centre for Neuroscience and Regenerative Medicine, University of Technology Sydney, Ultimo, NSW, Australia.7Institut Guttmann, Hospital de Neurorehabilitació, Institut Universitari Adscrit a la Universitat Autònoma de Barcelona, Barcelona, Spain.6Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, United States.5Department of Neurosurgery, University of California, Los Angeles, Los Angeles, CA, United States.4Department of Neurobiology, University of California, Los Angeles, Los Angeles, CA, United States.3Institute of Urology, Keck School of Medicine of University of Southern California, Los Angeles, CA, United States. ![]() ![]() 2Rancho Los Amigos National Rehabilitation Center, Downey, CA, United States.1Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States.Gad 1,2 Evgeniy Kreydin 2,3 Hui Zhong 1,2 Kyle Latack 2,3 V.
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